Endocrine Abstracts

Introduction: Amiodarone induced thyrotoxicosis (AIT) occurs in 5–10% of patients and may occur at any time throughout the course of treatment including months after discontinuation. Two distinct forms of AIT are distinguished and treated differently. Iodine-induced hyperthyroidism, typically seen in patients with underlying thyroid disease, is referred to as typ1 AIT and treated with high doses of thionamide antithyroid drugs and perchlorate. Type 2 AIT is a destructive ...

Background: This study prospectively assessed the sensitivity and positive predictive value (PPV) of ultrasound (US), ultrasound-guided fine needle aspiration with PTH measurement in the needle washout (US-FNA) and sestamibi scintigraphy (SS) for the localisation of parathyroid adenomas in patients with primary hyperparathyroidism (pHPT) and features of uniglandular disease.Methods: 51 consecutive patients with pHPT referred for first time surgery with a...

Background: Recent guidelines recommend lobectomy (LOB) when compared to total thyroidectomy (TTX) as the preferred approach for patients with low-risk differentiated thyroid cancer (DTC). Major advantages are the avoidance of lifelong hormone replacement therapy and the absence of any risk for contralateral recurrent laryngeal nerve palsy and postoperative hypoparathyroidism with no or minimal increased risk for adverse oncological outcomes. However, this limited approached s...

Background: Focused parathyroidectomy has become the standard procedure for patients with sporadic primary hyperparathyroidism (pHPT) fulfilling the criteria for surgical therapy and requires preoperative localization procedures. Ultrasound imaging (US) and 99mTc-sestamibi-scintigraphy with/without SPECT/CT (SC) are established first line procedures. 18F-choline PET/CT (PET) has emerged as a novel sensitive and specific method. However, current reimbursem...